Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EGF-containing fibulin-like extracellular matrix protein 1 (111-160 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EFEMP1 |
Gene ID: |
2202 |
Uniprot ID: |
FBLN3_HUMAN |
Immunogen Region: |
111-160 aa |
Specificity: |
Fibulin-3 Polyclonal Antibody detects endogenous levels of Fibulin-3 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human EFEMP1 at the amino acid range 111-160 |
Function | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
Protein Name | Egf-Containing Fibulin-Like Extracellular Matrix Protein 1Extracellular Protein S1-5Fibrillin-Like ProteinFibulin-3Fibl-3 |
Database Links | Reactome: R-HSA-2129379 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalizes To The Lamina Propria Underneath The Olfactory Epithelium |
Alternative Antibody Names | Anti-Egf-Containing Fibulin-Like Extracellular Matrix Protein 1 antibodyAnti-Extracellular Protein S1-5 antibodyAnti-Fibrillin-Like Protein antibodyAnti-Fibulin-3 antibodyAnti-Fibl-3 antibodyAnti-EFEMP1 antibodyAnti-FBLN3 antibodyAnti-FBNL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance