Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
EFCAB7 |
Gene ID: |
84455 |
Uniprot ID: |
EFCB7_HUMAN |
Immunogen Region: |
170-400 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 170-400 of human EFCAB7 (NP_115813.2). |
Immunogen Sequence: |
TNEQCLKTTLEKLEVDSKLM RHQFGNHIEGSPERDPSPVP KPSPKITRKTDPETFLNKGD TRSSLLSATRKFKTSVSFTV TMGANGNRNSKLMEPNLIKD WQHMQSKGCFFLEEDGEIIS HQYRMQIAQRSMVYLTIKPL NLSQVEGKPSPWLSVDTALY ILKENESQANLQLVCFTELR NREVFGWTGELGPGIYWLIP STTGCRLRKKIKPVTDEAQL VYRDETGELFL |
Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. |
Protein Name | Ef-Hand Calcium-Binding Domain-Containing Protein 7 |
Database Links | Reactome: R-HSA-5635838 |
Cellular Localisation | Cell ProjectionCilium MembranePeripheral Membrane ProteinCytoplasmic SideThe Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
Alternative Antibody Names | Anti-Ef-Hand Calcium-Binding Domain-Containing Protein 7 antibodyAnti-EFCAB7 antibodyAnti-KIAA1799 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance