| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | EFCAB7 |
| Gene ID: | 84455 |
| Uniprot ID: | EFCB7_HUMAN |
| Immunogen Region: | 170-400 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-400 of human EFCAB7 (NP_115813.2). |
| Immunogen Sequence: | TNEQCLKTTLEKLEVDSKLM RHQFGNHIEGSPERDPSPVP KPSPKITRKTDPETFLNKGD TRSSLLSATRKFKTSVSFTV TMGANGNRNSKLMEPNLIKD WQHMQSKGCFFLEEDGEIIS HQYRMQIAQRSMVYLTIKPL NLSQVEGKPSPWLSVDTALY ILKENESQANLQLVCFTELR NREVFGWTGELGPGIYWLIP STTGCRLRKKIKPVTDEAQL VYRDETGELFL |
| Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. |
| Protein Name | Ef-Hand Calcium-Binding Domain-Containing Protein 7 |
| Database Links | Reactome: R-HSA-5635838 |
| Cellular Localisation | Cell ProjectionCilium MembranePeripheral Membrane ProteinCytoplasmic SideThe Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
| Alternative Antibody Names | Anti-Ef-Hand Calcium-Binding Domain-Containing Protein 7 antibodyAnti-EFCAB7 antibodyAnti-KIAA1799 antibody |
Information sourced from Uniprot.org