Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:200-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EEF1E1 |
Gene ID: | 9521 |
Uniprot ID: | MCA3_HUMAN |
Immunogen Region: | 1-100 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EEF1E1 (NP_004271.1). |
Immunogen Sequence: | MAAAAELSLLEKSLGLSKGN KYSAQGERQIPVLQTNNGPS LTGLTTIAAHLVKQANKEYL LGSTAEEKAIVQQWLEYRVT QVDGHSSKNDIHTLLKDLNS |
Tissue Specificity | Down-regulated in various cancer tissues. |
Function | Positive modulator of ATM response to DNA damage. |
Protein Name | Eukaryotic Translation Elongation Factor 1 Epsilon-1Aminoacyl Trna Synthetase Complex-Interacting Multifunctional Protein 3Elongation Factor P18Multisynthase Complex Auxiliary Component P18 |
Database Links | Reactome: R-HSA-2408522Reactome: R-HSA-379716Reactome: R-HSA-9856649 |
Cellular Localisation | CytoplasmCytosolNucleusCytoplasmic Under Growth Arrest ConditionsTranslocated Into The Nucleus When Growth Resumes (S Phase) And Following Dna Damage |
Alternative Antibody Names | Anti-Eukaryotic Translation Elongation Factor 1 Epsilon-1 antibodyAnti-Aminoacyl Trna Synthetase Complex-Interacting Multifunctional Protein 3 antibodyAnti-Elongation Factor P18 antibodyAnti-Multisynthase Complex Auxiliary Component P18 antibodyAnti-EEF1E1 antibodyAnti-AIMP3 antibodyAnti-P18 antibody |
Information sourced from Uniprot.org