| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EEF1A2 |
| Gene ID: | 1917 |
| Uniprot ID: | EF1A2_HUMAN |
| Immunogen Region: | 184-463 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 184-463 of human EEF1A2 (NP_001949.1). |
| Immunogen Sequence: | NPATVPFVPISGWHGDNMLE PSPNMPWFKGWKVERKEGNA SGVSLLEALDTILPPTRPTD KPLRLPLQDVYKIGGIGTVP VGRVETGILRPGMVVTFAPV NITTEVKSVEMHHEALSEAL PGDNVGFNVKNVSVKDIRRG NVCGDSKSDPPQEAAQFTSQ VIILNHPGQISAGYSPVIDC HTAHIACKFAELKEKIDRRS GKKLEDNPKSLKSGDAAIVE MVPGKPMCVESFSQYPPLG |
| Tissue Specificity | Brain, heart, and skeletal muscle. |
| Post Translational Modifications | Trimethylated at Lys-165 by EEF1AKMT3. Mono-, di-, and trimethylated at Lys-36 by EEF1AKMT4.trimethylated form is predominant. Methylation by EEF1AKMT4 contributes to the fine-tuning of translation rates for a subset of tRNAs. Trimethylated at the N-terminus by METTL13. Mono- and dimethylated at Lys-55 by METTL13.dimethylated form is predominant. |
| Function | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. |
| Protein Name | Elongation Factor 1-Alpha 2Ef-1-Alpha-2Eukaryotic Elongation Factor 1 A-2Eef1a-2Statin-S1 |
| Database Links | Reactome: R-HSA-156842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Elongation Factor 1-Alpha 2 antibodyAnti-Ef-1-Alpha-2 antibodyAnti-Eukaryotic Elongation Factor 1 A-2 antibodyAnti-Eef1a-2 antibodyAnti-Statin-S1 antibodyAnti-EEF1A2 antibodyAnti-EEF1AL antibodyAnti-STN antibody |
Information sourced from Uniprot.org
