| Host: | Mouse |
| Applications: | WB/ICC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Early Endosome antigen 1 (N-Term) is suitable for use in Western Blot and Immunocytochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | M347 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: | Antigen Affinity Purified |
| Dilution Range: | WB 1:1000ICC 1:50 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EEA1 |
| Gene ID: | 8411 |
| Uniprot ID: | EEA1_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | This antibody detects a 180 kDa* protein corresponding to the apparent molecular mass of EEA1 on SDS-PAGE immunoblots of adult mouse brain. In immunocytochemistry, anti-EEA1 specifically stains endosomal vesicles. |
| Immunogen: | Clone M347 was generated from a recombinant protein corresponding to amino acid residues in the N-terminal region of human EEA1. This sequence has high homology to similar regions in rat and mouse EEA1. |
| Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
| Protein Name | Early Endosome Antigen 1Endosome-Associated Protein P162Zinc Finger Fyve Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-168138 |
| Cellular Localisation | CytoplasmEarly Endosome MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Early Endosome Antigen 1 antibodyAnti-Endosome-Associated Protein P162 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 2 antibodyAnti-EEA1 antibodyAnti-ZFYVE2 antibody |
Information sourced from Uniprot.org