| Host: | Goat |
| Applications: | WB/IF/IHC-F |
| Reactivity: | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal anti-Early Endosome antigen 1 (1230aa C-Term) for use in WB, IF and IHC-F in Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep and Simian samples. Datasheet inc |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Concentration: | 3 mg/mL |
| Dilution Range: | WB 1:250-1:1000IF 1:25-1:250IHC-F 1:100-1:500Ferreira JV Soares AR Ramalho J et al. Sci Adv 2022 Mar PMID: 35333565Ernst K Landenberger M Nieland J et al. Toxins-Basel 2021 May PMID: 34071730 |
| Storage Instruction: | For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in-20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Gene Symbol: | EEA1 |
| Gene ID: | 8411 |
| Uniprot ID: | EEA1_HUMAN |
| Immunogen Region: | 1230aa C-Term |
| Accession Number: | ENSG00000102189 |
| Specificity: | Detects a band of 180 kDa by Western blot in the following human, mouse and rat whole cell lysates. |
| Immunogen: | Purified recombinant peptide within residues 1230 aa to the C-terminus of human EEA1 produced in E. coli. |
| Immunogen Sequence: | KKHEENEAKLTMQITALNEN KHEENEAKLTMQITALNENL HEENEAKLTMQITALNENLG EENEAKLTMQITALNENLGT ENEAKLTMQITALNENLGTV NEAKLTMQITALNENLGTVK EAKLTMQITALNENLGTVKK AKLTMQITALNENLGTVKKE KLTMQITALNENLGTVKKEW LTMQITALNENLGTVKKEWQ |
| Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
| Protein Name | Early Endosome Antigen 1Endosome-Associated Protein P162Zinc Finger Fyve Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-168138 |
| Cellular Localisation | CytoplasmEarly Endosome MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Early Endosome Antigen 1 antibodyAnti-Endosome-Associated Protein P162 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 2 antibodyAnti-EEA1 antibodyAnti-ZFYVE2 antibody |
Information sourced from Uniprot.org
