| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-EDNRA (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | EDNRA |
| Gene ID: | 1909 |
| Uniprot ID: | EDNRA_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for EDNRA. |
| Immunogen: | A synthetic peptide from c-terminal region of human Endothelin-1 receptor (EDNRA) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
| Protein Name | Endothelin-1 ReceptorEndothelin Receptor Type AEt-AEta-RHet-Ar |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Endothelin-1 Receptor antibodyAnti-Endothelin Receptor Type A antibodyAnti-Et-A antibodyAnti-Eta-R antibodyAnti-Het-Ar antibodyAnti-EDNRA antibodyAnti-ETA antibodyAnti-ETRA antibody |
Information sourced from Uniprot.org