Host: |
Rabbit |
Applications: |
IHC |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-EDN3 (17-238) is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IHC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EDN3 |
Gene ID: |
1908 |
Uniprot ID: |
EDN3_HUMAN |
Immunogen Region: |
17-238 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 17-238 of human EDN3 (NP_996917.1). |
Immunogen Sequence: |
AGFVPCSQSGDAGRRGVSQA PTAARSEGDCEETVAGPGEE TVAGPGEGTVAPTALQGPSP GSPGQEQAAEGAPEHHRSRR CTCFTYKDKECVYYCHLDII WINTPEQTVPYGLSNYRGSF RGKRSAGPLPGNLQLSHRPH LRCACVGRYDKACLHFCTQT LDVSSNSRTAEKTDKEEEGK VEVKDQQSKQALDLHHPKLM PGSGLALAPSTCPRCLFQEG AP |
Tissue Specificity | Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells. |
Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
Protein Name | Endothelin-3Et-3Preproendothelin-3Ppet3 |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Endothelin-3 antibodyAnti-Et-3 antibodyAnti-Preproendothelin-3 antibodyAnti-Ppet3 antibodyAnti-EDN3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance