| Tissue Specificity | Detected in fetal kidney, lung, skin and cultured neonatal epidermal keratinocytes. Not detected in lymphoblast and fibroblast cell lines. |
| Function | Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member EdarAnhidrotic Ectodysplasin Receptor 1Downless HomologEda-A1 ReceptorEctodermal Dysplasia ReceptorEctodysplasin-A Receptor |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member Edar antibodyAnti-Anhidrotic Ectodysplasin Receptor 1 antibodyAnti-Downless Homolog antibodyAnti-Eda-A1 Receptor antibodyAnti-Ectodermal Dysplasia Receptor antibodyAnti-Ectodysplasin-A Receptor antibodyAnti-EDAR antibodyAnti-DL antibody |
Information sourced from Uniprot.org
