Post Translational Modifications | May be heavily O-glycosylated. |
Function | Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. |
Protein Name | Endothelial Cell-Specific Chemotaxis RegulatorApoptosis Regulator Through Modulating Iap ExpressionAriaEndothelial Cell-Specific Molecule 2 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
Alternative Antibody Names | Anti-Endothelial Cell-Specific Chemotaxis Regulator antibodyAnti-Apoptosis Regulator Through Modulating Iap Expression antibodyAnti-Aria antibodyAnti-Endothelial Cell-Specific Molecule 2 antibodyAnti-ECSCR antibodyAnti-ECSM2 antibody |
Information sourced from Uniprot.org