Anti-ECM1 antibody (280-405) (STJ118796)

Name: Anti-ECM1 antibody (280-405) (STJ118796)
SKU: STJ118796
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118796

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Short Description	Rabbit polyclonal ECM1 (280-405) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ECM1
Gene ID	1893
Uniprot ID	ECM1_HUMAN
Immunogen Region	280-405
Immunogen Sequence	QLRACPSHQPDISSGLELPF PPGVPTLDNIKNICHLRRFR SVPRNLPATDPLQRELLALI QLEREFQRCCRQGNNHTCTW KAWEDTLDKYCDREYAVKTH HHLCCRHPPSPTRDECFARR APYPNY
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 280-405 of human ECM1 (NP_004416.2).

Tissue Specificity	Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin.wide expression is observed throughout the dermis with minimal expression in the epidermis.
Function	Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
Protein Name	Extracellular Matrix Protein 1 Secretory Component P85
Database Links	Reactome: R-HSA-114608
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Extracellular Matrix Protein 1 antibody Anti-Secretory Component P85 antibody Anti-ECM1 antibody

Information sourced from Uniprot.org