| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ECI1 |
| Gene ID: | 1632 |
| Uniprot ID: | ECI1_HUMAN |
| Immunogen Region: | 63-302 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 63-302 of human ECI1 (NP_001910.2). |
| Immunogen Sequence: | KNPPVNSLSLEFLTELVISL EKLENDKSFRGVILTSDRPG VFSAGLDLTEMCGRSPAHYA GYWKAVQELWLRLYQSNLVL VSAINGACPAGGCLVALTCD YRILADNPRYCIGLNETQLG IIAPFWLKDTLENTIGHRAA ERALQLGLLFPPAEALQVGI VDQVVPEEQVQSTALSAIAQ WMAIPDHARQLTKAMMRKAT ASRLVTQRDADVQNFVSFIS KDSIQKSLQMYLERLKEEK |
| Tissue Specificity | Expressed in liver (at protein level). |
| Function | Key enzyme of fatty acid beta-oxidation (Probable). Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs. The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length. |
| Protein Name | Enoyl-Coa Delta Isomerase 1 - Mitochondrial3 -2-Trans-Enoyl-Coa IsomeraseDelta(3 -Delta(2-Enoyl-Coa IsomeraseD3 -D2-Enoyl-Coa IsomeraseDodecenoyl-Coa Isomerase |
| Database Links | Reactome: R-HSA-77288Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Enoyl-Coa Delta Isomerase 1 - Mitochondrial antibodyAnti-3 -2-Trans-Enoyl-Coa Isomerase antibodyAnti-Delta(3 -Delta(2-Enoyl-Coa Isomerase antibodyAnti-D3 -D2-Enoyl-Coa Isomerase antibodyAnti-Dodecenoyl-Coa Isomerase antibodyAnti-ECI1 antibodyAnti-DCI antibody |
Information sourced from Uniprot.org