![Anti-EBV-EA-p50-55 antibody [1108-1] (STJ16100758)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149475/302379/STJ16100758_1__40677.1646940565.jpg?c=1 "Anti-EBV-EA-p50-55 antibody [1108-1] (STJ16100758)")
![Anti-EBV-EA-p50-55 antibody [1108-1] (STJ16100758)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149475/302379/STJ16100758_1__40677.1646940565.jpg?c=1 "Anti-EBV-EA-p50-55 antibody [1108-1] (STJ16100758)")
| Host: | Mouse |
| Applications: | FC/IF/IHC/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-EBV-EA-p50-55 is suitable for use in Flow Cytometry, Immunofluorescence, Immunohistochemistry and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 1108-1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Purification: | Affinity purified from tissue culture. |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Dilution Range: | Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 minutes at RT; for staining of formalin-fixed tissues no suitable antigen retrieval method is known to date). Immunopre |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: | HCN3 |
| Gene ID: | 57657 |
| Uniprot ID: | HCN3_HUMAN |
| Immunogen: | A BALB/c mouse was immunized with immunoprecipitated EBV early antigens. Fusion partner: NS-0. |
| Tissue Specificity | Detected in brain. |
| Function | Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions, with an about 3:1 preference for potassium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). In particular, plays a pivotal role in maintaining excitability and promoting rhythmic burst firing within hypothalamic nuclei. Exerts a significant influence on the configuration of the cardiac action potential waveform. Does not appear to play a prominent role in the processing of acute, neuropathic, or inflammatory pain. |
| Protein Name | Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 |
| Database Links | Reactome: R-HSA-1296061 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 antibodyAnti-HCN3 antibodyAnti-KIAA1535 antibody |
Information sourced from Uniprot.org