Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
EARS2 |
Gene ID: |
124454 |
Uniprot ID: |
SYEM_HUMAN |
Immunogen Region: |
42-220 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 42-220 of human EARS2 (NP_001295140.1). |
Immunogen Sequence: |
APSPTGFLHLGGLRTALYNY IFAKKYQGSFILRLEDTDQT RVVPGAAENIEDMLEWAGIP PDESPRRGGPAGPYQQSQRL ELYAQATEALLKTGAAYPCF CSPQRLELLKKEALRNHQTP RYDNRCRNMSQEQVAQKLAK DPKPAIRFRLEQVVPAFQDL VYGWNRHEVASVEGDPVIM |
Function | Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity. |
Protein Name | Nondiscriminating Glutamyl-Trna Synthetase Ears2 - MitochondrialGlutamate--Trna(Gln Ligase Ears2 - MitochondrialGlutamyl-Trna SynthetaseGlursMitochondrial Glutamyl-Trna SynthetaseMtglurs |
Database Links | Reactome: R-HSA-379726 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Nondiscriminating Glutamyl-Trna Synthetase Ears2 - Mitochondrial antibodyAnti-Glutamate--Trna(Gln Ligase Ears2 - Mitochondrial antibodyAnti-Glutamyl-Trna Synthetase antibodyAnti-Glurs antibodyAnti-Mitochondrial Glutamyl-Trna Synthetase antibodyAnti-Mtglurs antibodyAnti-EARS2 antibodyAnti-KIAA1970 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance