Anti-EAAT1 antibody (480-543) {Biotin} (STJ500832)

SKU:
STJ500832-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Monkey/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EAAT1 (480-543) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.61 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Slc1a3
Gene ID: 20512
Uniprot ID: EAA1_MOUSE
Immunogen Region: 480-543
Specificity: Will not cross react with EAAT2 protein.
Immunogen: Synthetic peptide corresponding to C terminal amino acids 480-543 of Mouse EAAT1 protein. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using heterobifunctional cross linker fo
Tissue Specificity Detected in brain, in Bergmann glia arborising into the molecular layer of the cerebellum (at protein level). Localized in brain and is highly enriched in the Purkinje cell layer in cerebellum. Intermediate level in lung, low level in spleen, skeletal muscle and testis.
Post Translational Modifications Glycosylated.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 1
Glial High Affinity Glutamate Transporter
High-Affinity Neuronal Glutamate Transporter
Glut-1
Sodium-Dependent Glutamate/Aspartate Transporter 1
Glast-1
Solute Carrier Family 1 Member 3
Database Links Reactome: R-MMU-210455
Reactome: -MMU-210500
Reactome: -MMU-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Excitatory Amino Acid Transporter 1 antibody
Anti-Glial High Affinity Glutamate Transporter antibody
Anti-High-Affinity Neuronal Glutamate Transporter antibody
Anti-Glut-1 antibody
Anti-Sodium-Dependent Glutamate/Aspartate Transporter 1 antibody
Anti-Glast-1 antibody
Anti-Solute Carrier Family 1 Member 3 antibody
Anti-Slc1a3 antibody
Anti-Eaat1 antibody
Anti-Gmt1 antibody

Information sourced from Uniprot.org

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