Anti-E2F3 antibody (70-120) (STJ500822)

SKU:
STJ500822-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-E2F3 (70-120) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.78-0.89 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: E2f3
Gene ID: 13557
Uniprot ID: E2F3_MOUSE
Immunogen Region: 70-120
Immunogen: Synthetic peptide taken within amino acid region 70-120 on E2F3 protein.
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters.
Protein Name Transcription Factor E2f3
E2f-3
Database Links Reactome: R-MMU-68911
Reactome: -MMU-69231
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor E2f3 antibody
Anti-E2f-3 antibody
Anti-E2f3 antibody

Information sourced from Uniprot.org

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