| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DYX1C1-Isoform a (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Lysates of COS1 transfected with full length recombinant Human DYX1C1 gave bands at approx 48kDa after 0.1µg/ml antibody staining. In addition, a minor band of 24kDa is detected consis |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DNAAF4 |
| Gene ID: | 161582 |
| Uniprot ID: | DAAF4_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_570722.2 |
| Specificity: | This antibody is expected to recognise only one of the three reported isoforms (NP_570722.2, isoform a). |
| Immunogen Sequence: | KIRNVIQGTELKS |
| Function | Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. |
| Protein Name | Dynein Axonemal Assembly Factor 4Dyslexia Susceptibility 1 Candidate Gene 1 Protein |
| Cellular Localisation | NucleusCytoplasmDynein Axonemal ParticleCell ProjectionNeuron Projection |
| Alternative Antibody Names | Anti-Dynein Axonemal Assembly Factor 4 antibodyAnti-Dyslexia Susceptibility 1 Candidate Gene 1 Protein antibodyAnti-DNAAF4 antibodyAnti-DYX1C1 antibodyAnti-EKN1 antibody |
Information sourced from Uniprot.org