| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYRK4 |
| Gene ID: | 8798 |
| Uniprot ID: | DYRK4_HUMAN |
| Immunogen Region: | 330-480 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1). |
| Immunogen Sequence: | TASRRQTFFDSKGFPKNITN NRGKKRYPDSKDLTMVLKTY DTSFLDFLRRCLVWEPSLRM TPDQALKHAWIHQSRNLKPQ PRPQTLRKSNSFFPSETRKD KVQGCHHSSRKADEITKETT EKTKDSPTKHVQHSGDQQDC LQHGADTVQLP |
| Post Translational Modifications | Autophosphorylation on Tyr-264 in the activation loop is required for kinase activity. |
| Function | Possible non-essential role in spermiogenesis. |
| Protein Name | Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 4 |
| Cellular Localisation | Isoform 1: Cytoplasm Isoform 4: Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 4 antibody Anti-DYRK4 antibody |
Information sourced from Uniprot.org