Anti-DYNLRB1 antibody (1-63) (STJ117391)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DYNLRB1 (1-63) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DYNLRB1 |
| Gene ID | 83658 |
| Uniprot ID | DLRB1_HUMAN |
| Immunogen Region | 1-63 |
| Immunogen Sequence | MDNPTTTQYASLMHSFILKA RSTVRDIDPQNDLTFLRIRS KKNEIMVAPDKDYFLIVIQN PTE |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1). |
Additional Info
| Tissue Specificity | High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
| Protein Name | Dynein Light Chain Roadblock-Type 1Bithoraxoid-Like ProteinBlpDynein Light Chain 2a - CytoplasmicDynein-Associated Protein Km23Roadblock Domain-Containing Protein 1 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Dynein Light Chain Roadblock-Type 1 antibodyAnti-Bithoraxoid-Like Protein antibodyAnti-Blp antibodyAnti-Dynein Light Chain 2a - Cytoplasmic antibodyAnti-Dynein-Associated Protein Km23 antibodyAnti-Roadblock Domain-Containing Protein 1 antibodyAnti-DYNLRB1 antibodyAnti-BITH antibodyAnti-DNCL2A antibodyAnti-DNLC2A antibodyAnti-ROBLD1 antibodyAnti-HSPC162 antibody |
Information sourced from Uniprot.org