| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYNLL2 |
| Gene ID: | 140735 |
| Uniprot ID: | DYL2_HUMAN |
| Immunogen Region: | 1-89 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_542408.1). |
| Immunogen Sequence: | MSDRKAVIKNADMSEDMQQD AVDCATQAMEKYNIEKDIAA YIKKEFDKKYNPTWHCIVGR NFGSYVTHETKHFIYFYLGQ VAILLFKSG |
| Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. |
| Protein Name | Dynein Light Chain 2 - Cytoplasmic8 Kda Dynein Light Chain BDlc8bDynein Light Chain Lc8-Type 2 |
| Database Links | Reactome: R-HSA-139910Reactome: R-HSA-141444Reactome: R-HSA-1632852Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-3371497Reactome: R-HSA-5620924Reactome: R-HSA-5663220Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-68877Reactome: R-HSA-9609690Reactome: R-HSA-9646399Reactome: R-HSA-9648025 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Dynein Light Chain 2 - Cytoplasmic antibodyAnti-8 Kda Dynein Light Chain B antibodyAnti-Dlc8b antibodyAnti-Dynein Light Chain Lc8-Type 2 antibodyAnti-DYNLL2 antibodyAnti-DLC2 antibody |
Information sourced from Uniprot.org
