| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DYNC2H1 |
| Gene ID: | 79659 |
| Uniprot ID: | DYHC2_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human DYNC2H1 (NP_001073932.1). |
| Immunogen Sequence: | MANGTADVRKLFIFTTTQNY FGLMSELWDQPLLCNCLEIN NFLDDGNQMLLRVQRSDAGI SFSNTIEFGDTKDKVLVFFK LRPEVITDENLHDNILVSSM LESPISSLYQAVRQVFAPML LKDQEWSRNFDPKLQNLLSE LEAGLGIVLRRSDTNLTKLK FKEDDTRGILTPSDEFQFWI EQAHRGNKQISKERANYFKE LFETIAREFYNLDSLSLLEV VDLVETTQDVVDDVWRQTE |
| Function | May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells. |
| Protein Name | Cytoplasmic Dynein 2 Heavy Chain 1Cytoplasmic Dynein 2 Heavy ChainDynein Cytoplasmic Heavy Chain 2Dynein Heavy Chain 11Hdhc11Dynein Heavy Chain Isotype 1b |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeCell MembranePeripheral Membrane ProteinLocalizes To The Apical CytoplasmIt Localizes To Golgi ApparatusCytoplasmic Vesicle And Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cytoplasmic Dynein 2 Heavy Chain 1 antibodyAnti-Cytoplasmic Dynein 2 Heavy Chain antibodyAnti-Dynein Cytoplasmic Heavy Chain 2 antibodyAnti-Dynein Heavy Chain 11 antibodyAnti-Hdhc11 antibodyAnti-Dynein Heavy Chain Isotype 1b antibodyAnti-DYNC2H1 antibodyAnti-DHC1B antibodyAnti-DHC2 antibodyAnti-DNCH2 antibodyAnti-DYH1B antibodyAnti-KIAA1997 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and ABCF2 knockout (KO) 293T cells, using [KO Validated] ABCF2 Rabbit polyclonal antibody (STJ11100825) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89761/358236/STJ11100825_1__22485.1713122568.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ABCF2 knockout (KO) 293T cells, using [KO Validated] ABCF2 Rabbit polyclonal antibody (STJ11100825) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.")
