Anti-DVL3 antibody (580-650) (STJ11103537)

Name: Anti-DVL3 antibody (580-650) (STJ11103537)
SKU: STJ11103537
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11103537

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Short Description	Rabbit polyclonal DVL3 (580-650) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	DVL3
Gene ID	1857
Uniprot ID	DVL3_HUMAN
Immunogen Region	580-650
Immunogen Sequence	RSGSDRRKEKDPKAGDSKSG GSGSESDHTTRSSLRGPRER APSERSGPAASEHSHRSHHS LASSLRSHHTH
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 580-650 of human DVL3 (NP_004414.3).

Post Translational Modifications	Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. Phosphorylated by CSNK1D. Arginine methylation may function as a switch in regulation of function in Wnt signaling.
Function	Involved in the signal transduction pathway mediated by multiple Wnt genes.
Protein Name	Segment Polarity Protein Dishevelled Homolog Dvl-3 Dishevelled-3 Dsh Homolog 3
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-201688 Reactome: R-HSA-4086400 Reactome: R-HSA-4641258 Reactome: R-HSA-4641262 Reactome: R-HSA-5368598 Reactome: R-HSA-5663220 Reactome: R-HSA-9673324
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Segment Polarity Protein Dishevelled Homolog Dvl-3 antibody Anti-Dishevelled-3 antibody Anti-Dsh Homolog 3 antibody Anti-DVL3 antibody Anti-KIAA0208 antibody

Information sourced from Uniprot.org