| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DUSP16 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Preliminary experiments gave no signal but low background in Human Brain and Jurkat lysates at up to 1µg/ml. We would appreciate any feedback from people in the field-have any results |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DUSP16 |
| Gene ID: | 80824 |
| Uniprot ID: | DUS16_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_085143.1 |
| Immunogen Sequence: | AHEMIGTQIVTER |
| Function | Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. |
| Protein Name | Dual Specificity Protein Phosphatase 16Mitogen-Activated Protein Kinase Phosphatase 7Map Kinase Phosphatase 7Mkp-7 |
| Database Links | Reactome: R-HSA-112409Reactome: R-HSA-5675221Reactome: R-HSA-9636569Reactome: R-HSA-9652817 |
| Cellular Localisation | CytoplasmNucleusCytoplasmic VesicleAfter Dissociation Upon Agtr StimulationRe-Associates With Arrb2 On Endocytic Vesicles |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 16 antibodyAnti-Mitogen-Activated Protein Kinase Phosphatase 7 antibodyAnti-Map Kinase Phosphatase 7 antibodyAnti-Mkp-7 antibodyAnti-DUSP16 antibodyAnti-KIAA1700 antibodyAnti-MKP7 antibody |
Information sourced from Uniprot.org
