| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DUSP12 |
| Gene ID: | 11266 |
| Uniprot ID: | DUS12_HUMAN |
| Immunogen Region: | 130-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-270 of human DUSP12 (NP_009171.1). |
| Immunogen Sequence: | LMKTDQLPFEKAYEKLQILK PEAKMNEGFEWQLKLYQAMG YEVDTSSAIYKQYRLQKVTE KYPELQNLPQELFAVDPTTV SQGLKDEVLYKCRKCRRSLF RSSSILDHREGSGPIAFAHK RMTPSSMLTTGRQAQCTSYF I |
| Tissue Specificity | Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung. |
| Function | Dual specificity phosphatase.can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates. |
| Protein Name | Dual Specificity Protein Phosphatase 12Dual Specificity Tyrosine Phosphatase Yvh1 |
| Cellular Localisation | NucleusCytoplasmCytosolPrimarily NuclearDetected In A Mesh-Like Pattern In The Cytosol |
| Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 12 antibodyAnti-Dual Specificity Tyrosine Phosphatase Yvh1 antibodyAnti-DUSP12 antibody |
Information sourced from Uniprot.org