• Western blot analysis of lysates from Jurkat cells, using MKP1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of Jurkat cells using MKP-1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MKP1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using MKP-1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-DUSP1 antibody (318-367) (STJ94136)

SKU:
STJ94136

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 1 (318-367) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DUSP1
Gene ID: 1843
Uniprot ID: DUS1_HUMAN
Immunogen Region: 318-367
Specificity: MKP-1 Polyclonal Antibody detects endogenous levels of MKP-1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human MKP1. AA range:318-367
Tissue Specificity Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Post Translational Modifications Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Function Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name Dual Specificity Protein Phosphatase 1
Dual Specificity Protein Phosphatase Hvh1
Mitogen-Activated Protein Kinase Phosphatase 1
Map Kinase Phosphatase 1
Mkp-1
Protein-Tyrosine Phosphatase Cl100
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-5675221
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 1 antibody
Anti-Dual Specificity Protein Phosphatase Hvh1 antibody
Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody
Anti-Map Kinase Phosphatase 1 antibody
Anti-Mkp-1 antibody
Anti-Protein-Tyrosine Phosphatase Cl100 antibody
Anti-DUSP1 antibody
Anti-CL100 antibody
Anti-MKP1 antibody
Anti-PTPN10 antibody
Anti-VH1 antibody

Information sourced from Uniprot.org

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