Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Dual oxidase 1 (1398-1448 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DUOX1 |
Gene ID: | 53905 |
Uniprot ID: | DUOX1_HUMAN |
Immunogen Region: | 1398-1448 aa |
Specificity: | This antibody detects endogenous levels of DUOX1 at Human/Rat |
Immunogen: | Synthesized peptide derived from the human DUOX1 at the amino acid range 1398-1448 |
Post Translational Modifications | N-glycosylated. |
Function | Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. |
Protein Name | Dual Oxidase 1Large Nox 1Long Nox 1Nadph Thyroid Oxidase 1Thyroid Oxidase 1 |
Database Links | Reactome: R-HSA-209968 |
Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinLocalizes To The Apical Membrane Of Epithelial Cells |
Alternative Antibody Names | Anti-Dual Oxidase 1 antibodyAnti-Large Nox 1 antibodyAnti-Long Nox 1 antibodyAnti-Nadph Thyroid Oxidase 1 antibodyAnti-Thyroid Oxidase 1 antibodyAnti-DUOX1 antibodyAnti-DUOX antibodyAnti-LNOX1 antibodyAnti-THOX1 antibody |
Information sourced from Uniprot.org