| Function | Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. |
| Protein Name | Dual Serine/Threonine And Tyrosine Protein KinaseDusty Protein KinaseDusty PkRip-Homologous KinaseReceptor-Interacting Serine/Threonine-Protein Kinase 5Sugen Kinase 496Sgk496 |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneApical Cell MembraneBasolateral Cell MembraneCell JunctionDetected At Apical Cell-Cell JunctionsColocalized With Fgf Receptors To The Cell MembraneDetected In Basolateral And Apical Membranes Of All Tubular Epithelia |
| Alternative Antibody Names | Anti-Dual Serine/Threonine And Tyrosine Protein Kinase antibodyAnti-Dusty Protein Kinase antibodyAnti-Dusty Pk antibodyAnti-Rip-Homologous Kinase antibodyAnti-Receptor-Interacting Serine/Threonine-Protein Kinase 5 antibodyAnti-Sugen Kinase 496 antibodyAnti-Sgk496 antibodyAnti-DSTYK antibodyAnti-KIAA0472 antibodyAnti-RIP5 antibodyAnti-RIPK5 antibodyAnti-SGK496 antibodyAnti-HDCMD38P antibody |
Information sourced from Uniprot.org
