Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | DSPP |
Gene ID: | 1834 |
Uniprot ID: | DSPP_HUMAN |
Immunogen Region: | 16-146 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 16-146 of human DSPP (NP_055023.2). |
Immunogen Sequence: | IPVPQSKPLERHVEKSMNLH LLARSNVSVQDELNASGTIK ESGVLVHEGDRGRQENTQDG HKGEGNGSKWAEVGGKSFST YSTLANEEGNIEGWNGDTGK AETYGHDGIHGKEENITANG IQGQVSIIDNA |
Tissue Specificity | Expressed in teeth. DPP is synthesized by odontoblast and transiently expressed by pre-ameloblasts. |
Post Translational Modifications | DSP is glycosylated. |
Function | DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals. |
Protein Name | Dentin Sialophosphoprotein Cleaved Into - Dentin Phosphoprotein Dentin Phosphophoryn Dpp - Dentin Sialoprotein Dsp |
Database Links | Reactome: R-HSA-3000178 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix |
Alternative Antibody Names | Anti-Dentin Sialophosphoprotein Cleaved Into - Dentin Phosphoprotein antibody Anti-Dentin Phosphophoryn antibody Anti-Dpp - Dentin Sialoprotein antibody Anti-Dsp antibody Anti-DSPP antibody |
Information sourced from Uniprot.org