Anti-DSC3 antibody (STJ193052)

SKU:
STJ193052
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Desmocollin-3 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
ELISA 1:5000-20000
Formulation:Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DSC3
Gene ID:1825
Uniprot ID:DSC3_HUMAN
Immunogen:Synthesized peptide derived from part of the human protein
Specificity:DSC3 Polyclonal Antibody detects endogenous levels of protein.
Function A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function. Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage. Essential for successful completion of embryo compaction and embryo development.
Protein Name Desmocollin-3
Cadherin Family Member 3
Desmocollin-4
Ht-Cp
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Cytoplasm
Expressed In The Cytoplasm And At The Cell Membrane Of Oocytes
Alternative Antibody Names Anti-Desmocollin-3 antibody
Anti-Cadherin Family Member 3 antibody
Anti-Desmocollin-4 antibody
Anti-Ht-Cp antibody
Anti-DSC3 antibody
Anti-CDHF3 antibody
Anti-DSC4 antibody

Information sourced from Uniprot.org

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