| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Desmocollin-3 (576-690) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DSC3 |
| Gene ID: |
1825 |
| Uniprot ID: |
DSC3_HUMAN |
| Immunogen Region: |
576-690 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 576-690 of human Desmocollin 3 (NP_001932.2). |
| Immunogen Sequence: |
EILQEYVVICKPKMGYTDIL AVDPDEPVHGAPFYFSLPNT SPEISRLWSLTKVNDTAARL SYQKNAGFQEYTIPITVKDR AGQAATKLLRVNLCECTHPT QCRATSRSTGVILGK |
| Tissue Specificity | Epidermis, buccal mucosa, esophagus and cervix. |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| Protein Name | Desmocollin-3Cadherin Family Member 3Desmocollin-4Ht-Cp |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
| Alternative Antibody Names | Anti-Desmocollin-3 antibodyAnti-Cadherin Family Member 3 antibodyAnti-Desmocollin-4 antibodyAnti-Ht-Cp antibodyAnti-DSC3 antibodyAnti-CDHF3 antibodyAnti-DSC4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Immunoprecipitation analysis of 200 Mu g extracts of A-549 cells using 3 Mu g [KD Validated] NF2 Rabbit polyclonal antibody (STJ115585). Western blot was performed from the immunoprecipitate using [KO Validated] NF2 Rabbit polyclonal antibody (STJ115585) at a dilition of 1:1000.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/94601/376322/STJ115585_1__30832.1713143345.jpg?c=1 "Immunoprecipitation analysis of 200 Mu g extracts of A-549 cells using 3 Mu g [KD Validated] NF2 Rabbit polyclonal antibody (STJ115585). Western blot was performed from the immunoprecipitate using [KO Validated] NF2 Rabbit polyclonal antibody (STJ115585) at a dilition of 1:1000.")