Anti-DSC1 antibody (749-799 aa) (STJ194228)

SKU:
STJ194228
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Desmocollin-1 (749-799 aa) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DSC1
Gene ID: 1823
Uniprot ID: DSC1_HUMAN
Immunogen Region: 749-799 aa
Specificity: This antibody detects endogenous levels of DSC1 at Human/Mouse
Immunogen: Synthesized peptide derived from the human DSC1 at the amino acid range 749-799
Function A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood.
Protein Name Desmocollin-1
Cadherin Family Member 1
Desmosomal Glycoprotein 2/3
Dg2/Dg3
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Desmosome
Alternative Antibody Names Anti-Desmocollin-1 antibody
Anti-Cadherin Family Member 1 antibody
Anti-Desmosomal Glycoprotein 2/3 antibody
Anti-Dg2/Dg3 antibody
Anti-DSC1 antibody
Anti-CDHF1 antibody

Information sourced from Uniprot.org