Anti-DRG2 antibody (150-260) (STJ119583)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DRG2 (150-260) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DRG2 |
| Gene ID | 1819 |
| Uniprot ID | DRG2_HUMAN |
| Immunogen Region | 150-260 |
| Immunogen Sequence | TKGEVQRSLLEKELESVGIR LNKHKPNIYFKPKKGGGISF NSTVTLTQCSEKLVQLILHE YKIFNAEVLFREDCSPDEFI DVIVGNRVYMPCLYVYNKID QISMEEVDRLA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human DRG2 (NP_001379.1). |
Additional Info
| Tissue Specificity | Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes. |
| Post Translational Modifications | Hydroxylated (with S stereochemistry) at C-3 of Lys-21 by JMJD7.this modification hinders trypsin-catalyzed proteolysis in vitro. Polyubiquitinated. |
| Function | Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. |
| Protein Name | Developmentally-Regulated Gtp-Binding Protein 2Drg-2Translation Factor Gtpase Drg2Trafac Gtpase Drg2 |
| Database Links | Reactome: R-HSA-9629569 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Developmentally-Regulated Gtp-Binding Protein 2 antibodyAnti-Drg-2 antibodyAnti-Translation Factor Gtpase Drg2 antibodyAnti-Trafac Gtpase Drg2 antibodyAnti-DRG2 antibody |
Information sourced from Uniprot.org