Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DRG2 (150-260) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DRG2 |
Gene ID: |
1819 |
Uniprot ID: |
DRG2_HUMAN |
Immunogen Region: |
150-260 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human DRG2 (NP_001379.1). |
Immunogen Sequence: |
TKGEVQRSLLEKELESVGIR LNKHKPNIYFKPKKGGGISF NSTVTLTQCSEKLVQLILHE YKIFNAEVLFREDCSPDEFI DVIVGNRVYMPCLYVYNKID QISMEEVDRLA |
Tissue Specificity | Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes. |
Post Translational Modifications | Hydroxylated (with S stereochemistry) at C-3 of Lys-21 by JMJD7.this modification hinders trypsin-catalyzed proteolysis in vitro. Polyubiquitinated. |
Function | Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. |
Protein Name | Developmentally-Regulated Gtp-Binding Protein 2Drg-2Translation Factor Gtpase Drg2Trafac Gtpase Drg2 |
Cellular Localisation | NucleusCytoplasm |
Alternative Antibody Names | Anti-Developmentally-Regulated Gtp-Binding Protein 2 antibodyAnti-Drg-2 antibodyAnti-Translation Factor Gtpase Drg2 antibodyAnti-Trafac Gtpase Drg2 antibodyAnti-DRG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance