Anti-DRD1 antibody (338-446) (STJ23428)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DRD1 (338-446) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DRD1 |
| Gene ID | 1812 |
| Uniprot ID | DRD1_HUMAN |
| Immunogen Region | 338-446 |
| Immunogen Sequence | RKAFSTLLGCYRLCPATNNA IETVSINNNGAAMFSSHHEP RGSISKECNLVYLIPHAVGS SEDLKKEEAAGIARPLEKLS PALSVILDYDTDVSLEKIQP ITQNGQHPT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1). |
Additional Info
| Tissue Specificity | Detected in caudate, nucleus accumbens and in the olfactory tubercle. |
| Function | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | D(1a Dopamine ReceptorDopamine D1 Receptor |
| Database Links | Reactome: R-HSA-390651Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneCell ProjectionCilium MembraneDendriteDendritic SpineTransport From The Endoplasmic Reticulum To The Cell Surface Is Regulated By Interaction With Dnajc14 |
| Alternative Antibody Names | Anti-D(1a Dopamine Receptor antibodyAnti-Dopamine D1 Receptor antibodyAnti-DRD1 antibody |
Information sourced from Uniprot.org