| Host: | Rabbit |
| Applications: | ELISA/ICC/WB |
| Reactivity: | Bovine/Chicken/Human/Monkey/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-DRAXIN (300-330) is suitable for use in ELISA, Immunocytochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.64 µg/µl |
| Dilution Range: | WB: 1:500-1:1, 000DB: 1:20, 000-1:50, 000ELISA: 1:20, 000-1:50, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DRAXIN |
| Gene ID: | 374946 |
| Uniprot ID: | DRAXI_HUMAN |
| Immunogen Region: | 300-330 |
| Immunogen: | Synthetic peptide taken within amino acid region 300-330 on C terminal region of Human Draxin protein. Region: NNKCFDDCMC VEGLRCYAKF HRNRRVTRRK |
| Function | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
| Protein Name | DraxinDorsal Inhibitory Axon Guidance ProteinDorsal Repulsive Axon Guidance ProteinNeucrin |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Draxin antibodyAnti-Dorsal Inhibitory Axon Guidance Protein antibodyAnti-Dorsal Repulsive Axon Guidance Protein antibodyAnti-Neucrin antibodyAnti-DRAXIN antibodyAnti-C1orf187 antibodyAnti-PSEC0258 antibodyAnti-UNQ3119 antibodyAnti-PRO10268 antibody |
Information sourced from Uniprot.org
