| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DRAM2 (200-267 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB. Use at a dilution of 1:200 to 1:2000. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
Dram2 |
| Gene ID: |
67171 |
| Uniprot ID: |
DRAM2_MOUSE |
| Immunogen Region: |
200-267 aa |
| Specificity: |
Specific for DRAM2. |
| Immunogen: |
A synthetic peptide from aa region 200-267 of mouse DRAM2 conjugated to blue carrier protein has been used as the antigen. |
| Function | Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1. |
| Protein Name | Dna Damage-Regulated Autophagy Modulator Protein 2Transmembrane Protein 77 |
| Cellular Localisation | Lysosome MembraneMulti-Pass Membrane ProteinPhotoreceptor Inner SegmentApical Cell MembraneLocalized To Photoreceptor Inner Segments And To The Apical Surface Of Retinal Pigment Epithelial Cells |
| Alternative Antibody Names | Anti-Dna Damage-Regulated Autophagy Modulator Protein 2 antibodyAnti-Transmembrane Protein 77 antibodyAnti-Dram2 antibodyAnti-Tmem77 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
