Anti-DPYSL3 antibody (440-520) (STJ114169)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DPYSL3 (440-520) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DPYSL3 |
| Gene ID | 1809 |
| Uniprot ID | DPYL3_HUMAN |
| Immunogen Region | 440-520 |
| Immunogen Sequence | RGAPLVVICQGKIMLEDGNL HVTQGAGRFIPCSPFSDYVY KRIKARRKMADLHAVPRGMY DGPVFDLTTTPKGGTPAGSA R |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 440-520 of human DPYSL3 (NP_001378.1). |
Additional Info
| Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
| Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
| Protein Name | Dihydropyrimidinase-Related Protein 3Drp-3Collapsin Response Mediator Protein 4Crmp-4Unc-33-Like Phosphoprotein 1Ulip-1 |
| Database Links | Reactome: R-HSA-399956 |
| Cellular Localisation | CytoplasmCell ProjectionGrowth ConeColocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
| Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibodyAnti-Drp-3 antibodyAnti-Collapsin Response Mediator Protein 4 antibodyAnti-Crmp-4 antibodyAnti-Unc-33-Like Phosphoprotein 1 antibodyAnti-Ulip-1 antibodyAnti-DPYSL3 antibodyAnti-CRMP4 antibodyAnti-DRP3 antibodyAnti-ULIP antibodyAnti-ULIP1 antibody |
Information sourced from Uniprot.org