Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Dihydropyrimidinase-related protein 3 (240-290 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DPYSL3 |
Gene ID: | 1809 |
Uniprot ID: | DPYL3_HUMAN |
Immunogen Region: | 240-290 aa |
Specificity: | This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat |
Immunogen: | Synthesized peptide derived from the human DPYL3 at the amino acid range 240-290 |
Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
Protein Name | Dihydropyrimidinase-Related Protein 3 Drp-3 Collapsin Response Mediator Protein 4 Crmp-4 Unc-33-Like Phosphoprotein 1 Ulip-1 |
Database Links | Reactome: R-HSA-399956 |
Cellular Localisation | Cytoplasm Cell Projection Growth Cone Colocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibody Anti-Drp-3 antibody Anti-Collapsin Response Mediator Protein 4 antibody Anti-Crmp-4 antibody Anti-Unc-33-Like Phosphoprotein 1 antibody Anti-Ulip-1 antibody Anti-DPYSL3 antibody Anti-CRMP4 antibody Anti-DRP3 antibody Anti-ULIP antibody Anti-ULIP1 antibody |
Information sourced from Uniprot.org