Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Dihydropyrimidinase-related protein 3 (240-290 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DPYSL3 |
Gene ID: |
1809 |
Uniprot ID: |
DPYL3_HUMAN |
Immunogen Region: |
240-290 aa |
Specificity: |
This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human DPYL3 at the amino acid range 240-290 |
Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
Protein Name | Dihydropyrimidinase-Related Protein 3Drp-3Collapsin Response Mediator Protein 4Crmp-4Unc-33-Like Phosphoprotein 1Ulip-1 |
Database Links | Reactome: R-HSA-399956 |
Cellular Localisation | CytoplasmCell ProjectionGrowth ConeColocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibodyAnti-Drp-3 antibodyAnti-Collapsin Response Mediator Protein 4 antibodyAnti-Crmp-4 antibodyAnti-Unc-33-Like Phosphoprotein 1 antibodyAnti-Ulip-1 antibodyAnti-DPYSL3 antibodyAnti-CRMP4 antibodyAnti-DRP3 antibodyAnti-ULIP antibodyAnti-ULIP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance