| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DPYD |
| Gene ID: | 1806 |
| Uniprot ID: | DPYD_HUMAN |
| Immunogen Region: | 1-173 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_000101.2). |
| Immunogen Sequence: | MAPVLSKDSADIESILALNP RTQTHATLCSTSAKKLDKKH WKRNPDKNCFNCEKLENNFD DIKHTTLGERGALREAMRCL KCADAPCQKSCPTNLDIKSF ITSIANKNYYGAAKMIFSDN PLGLTCGMVCPTSDLCVGGC NLYATEEGPINIGGLQQFAT ETLILAFSLMNHL |
| Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
| Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
| Protein Name | Dihydropyrimidine Dehydrogenase Nadp(+DhpdhaseDpdDihydrothymine DehydrogenaseDihydrouracil Dehydrogenase |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dihydropyrimidine Dehydrogenase Nadp(+ antibodyAnti-Dhpdhase antibodyAnti-Dpd antibodyAnti-Dihydrothymine Dehydrogenase antibodyAnti-Dihydrouracil Dehydrogenase antibodyAnti-DPYD antibody |
Information sourced from Uniprot.org