Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DPM1 |
Gene ID: | 8813 |
Uniprot ID: | DPM1_HUMAN |
Immunogen Region: | 1-260 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DPM1 (NP_003850.1). |
Immunogen Sequence: | MASLEVSRSPRRSRRELEVR SPRQNKYSVLLPTYNERENL PLIVWLLVKSFSESGINYEI IIIDDGSPDGTRDVAEQLEK IYGSDRILLRPREKKLGLGT AYIHGMKHATGNYIIIMDAD LSHHPKFIPEFIRKQKEGNF DIVSGTRYKGNGGVYGWDLK RKIISRGANFLTQILLRPGA SDLTGSFRLYRKEVLEKLIE KCVSKGYVFQMEMIVRARQL NYTIGEVPISFVDRVYGES |
Function | Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex. |
Protein Name | Dolichol-Phosphate Mannosyltransferase Subunit 1Dolichol-Phosphate Mannose Synthase Subunit 1Dpm Synthase Subunit 1Dolichyl-Phosphate Beta-D-Mannosyltransferase Subunit 1Mannose-P-Dolichol Synthase Subunit 1Mpd Synthase Subunit 1 |
Database Links | Reactome: R-HSA-162699Reactome: R-HSA-4717374Reactome: R-HSA-4719360Reactome: R-HSA-4719377 |
Cellular Localisation | Endoplasmic Reticulum |
Alternative Antibody Names | Anti-Dolichol-Phosphate Mannosyltransferase Subunit 1 antibodyAnti-Dolichol-Phosphate Mannose Synthase Subunit 1 antibodyAnti-Dpm Synthase Subunit 1 antibodyAnti-Dolichyl-Phosphate Beta-D-Mannosyltransferase Subunit 1 antibodyAnti-Mannose-P-Dolichol Synthase Subunit 1 antibodyAnti-Mpd Synthase Subunit 1 antibodyAnti-DPM1 antibody |
Information sourced from Uniprot.org