| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-2-3-amino-3-carboxypropylhistidine synthase subunit 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DPH2 |
| Gene ID: |
1802 |
| Uniprot ID: |
DPH2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of DPH2 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human DPH2 |
| Function | Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit. |
| Protein Name | 2-(3-Amino-3-Carboxypropylhistidine Synthase Subunit 2Diphthamide Biosynthesis Protein 2Diphtheria Toxin Resistance Protein 2S-Adenosyl-L-Methionine -L-Histidine 3-Amino-3-Carboxypropyltransferase 2 |
| Database Links | Reactome: R-HSA-5358493 |
| Alternative Antibody Names | Anti-2-(3-Amino-3-Carboxypropylhistidine Synthase Subunit 2 antibodyAnti-Diphthamide Biosynthesis Protein 2 antibodyAnti-Diphtheria Toxin Resistance Protein 2 antibodyAnti-S-Adenosyl-L-Methionine -L-Histidine 3-Amino-3-Carboxypropyltransferase 2 antibodyAnti-DPH2 antibodyAnti-DPH2L2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
