Function | Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. |
Protein Name | Dipeptidase 1Beta-LactamaseDehydropeptidase-IMicrosomal DipeptidaseRenal DipeptidaseHrdp |
Database Links | Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535 |
Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorCell ProjectionMicrovillus MembraneBrush Border Membrane |
Alternative Antibody Names | Anti-Dipeptidase 1 antibodyAnti-Beta-Lactamase antibodyAnti-Dehydropeptidase-I antibodyAnti-Microsomal Dipeptidase antibodyAnti-Renal Dipeptidase antibodyAnti-Hrdp antibodyAnti-DPEP1 antibodyAnti-MDP antibodyAnti-RDP antibody |
Information sourced from Uniprot.org