• Western blot analysis of extracts of various cell lines, using DPEP1 antibody (STJ28211) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-DPEP1 antibody (17-385) (STJ28211)

SKU:
STJ28211

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DPEP1 (17-385) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DPEP1
Gene ID: 1800
Uniprot ID: DPEP1_HUMAN
Immunogen Region: 17-385
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-385 of human DPEP1 (NP_001121613.1).
Immunogen Sequence: DFFRDEAERIMRDSPVIDGH NDLPWQLLDMFNNRLQDERA NLTTLAGTHTNIPKLRAGFV GGQFWSVYTPCDTQNKDAVR RTLEQMDVVHRMCRMYPETF LYVTSSAGIRQAFREGKVAS LIGVEGGHSIDSSLGVLRAL YQLGMRYLTLTHSCNTPWAD NWLVDTGDSEPQSQGLSPFG QRVVKELNRLGVLIDLAHVS VATMKATLQLSRAPVIFSHS SAYSVCASRRNVPDDVLRL
Tissue Specificity Expressed in lung and kidneys.
Function Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
Protein Name Dipeptidase 1
Beta-Lactamase
Dehydropeptidase-I
Microsomal Dipeptidase
Renal Dipeptidase
Hrdp
Database Links Reactome: R-HSA-2142691
Reactome: R-HSA-5423646
Reactome: R-HSA-9664535
Cellular Localisation Apical Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Projection
Microvillus Membrane
Brush Border Membrane
Alternative Antibody Names Anti-Dipeptidase 1 antibody
Anti-Beta-Lactamase antibody
Anti-Dehydropeptidase-I antibody
Anti-Microsomal Dipeptidase antibody
Anti-Renal Dipeptidase antibody
Anti-Hrdp antibody
Anti-DPEP1 antibody
Anti-MDP antibody
Anti-RDP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance