• Immunohistochemistry with Anti-Dopamine Receptor D4 Antibody (STJ500717) of Rat brain at 1:250 dilution in buffer.

Anti-Dopamine Receptor D4 antibody (STJ500717)

SKU:
STJ500717-100

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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dopamine Receptor D4 is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:1, 000-1:1, 5000
DB: 1:50, 000
ELISA: 1:50, 000
IP: 1:200
IHC: 1:250
ICC: 1:250
IF: 1:250
CFM: 1:250
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Drd4
Gene ID: 13491
Uniprot ID: DRD4_MOUSE
Immunogen: Synthetic peptide corresponding to unique sequence on Dopamine Receptor D4 protein.
Tissue Specificity Detected in olfactory bulb, hypothalamus, olfactory tubercle, brainstem and striatum.
Post Translational Modifications Palmitoylated. Palmitoylation of the C-terminal Cys is important for normal expression at the cell membrane.
Function Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells.
Protein Name D(4 Dopamine Receptor
D(2c Dopamine Receptor
Dopamine D4 Receptor
Database Links Reactome: R-MMU-390651
Reactome: -MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-D(4 Dopamine Receptor antibody
Anti-D(2c Dopamine Receptor antibody
Anti-Dopamine D4 Receptor antibody
Anti-Drd4 antibody

Information sourced from Uniprot.org

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