Anti-Dopamine Receptor D3 antibody [R04-5P5] (STJA0036799)

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STJA0036799
€166.88 - €351.88
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Dopamine Receptor D3 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R04-5P5
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: DRD3
Gene ID: 1814
Uniprot ID: DRD3_HUMAN
Immunogen: A synthesized peptide derived from human Dopamine Receptor D3
Tissue Specificity Brain.
Post Translational Modifications Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Protein Name D(3 Dopamine Receptor
Dopamine D3 Receptor
Database Links Reactome: R-HSA-390651
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Both Membrane-Bound And Scattered In The Cytoplasm During Basal Conditions
Receptor Stimulation Results In The Rapid Internalization And Sequestration Of The Receptors At The Perinuclear Area (5 And 15 Minutes)
Followed By The Dispersal Of The Receptors To The Membrane (30 Minutes)
Drd3 And Grk4 Co-Localize In Lipid Rafts Of Renal Proximal Tubule Cells
Alternative Antibody Names Anti-D(3 Dopamine Receptor antibody
Anti-Dopamine D3 Receptor antibody
Anti-DRD3 antibody

Information sourced from Uniprot.org

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