| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-DOPA decarboxylase (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 50kDa band observed in Human Kidney lysates and 48kDa on Human Brain lysates (calculated MW of 53.9kDa according to NP_000781.1). Recommended concentration: 0.03-0.1µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | DDC |
| Gene ID: | 1644 |
| Uniprot ID: | DDC_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_000781.1; NP_001229815.1; NP_001229816.1; NP_001229817.1; NP_001229818.1 |
| Specificity: | This antibody is expected to recognise isoforms 1, 2, 3, 4 and 5 (NP_000781.1; NP_001229815.1; NP_001229816.1; NP_001229817.1; NP_001229818.1 respectively). Reported variants represent identical protein (NP_000781.1; NP_001076440.1). |
| Immunogen Sequence: | WEHIKELAADVL |
| Function | Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin. |
| Protein Name | Aromatic-L-Amino-Acid DecarboxylaseAadcDopa DecarboxylaseDdc |
| Database Links | Reactome: R-HSA-209905Reactome: R-HSA-209931 |
| Alternative Antibody Names | Anti-Aromatic-L-Amino-Acid Decarboxylase antibodyAnti-Aadc antibodyAnti-Dopa Decarboxylase antibodyAnti-Ddc antibodyAnti-DDC antibodyAnti-AADC antibody |
Information sourced from Uniprot.org