Anti-DOCK2 antibody (Internal) (STJ92757)

SKU:
STJ92757
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Dedicator of cytokinesis protein 2 (Internal) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:DOCK2
Gene ID:1794
Uniprot ID:DOCK2_HUMAN
Immunogen:Synthesized peptide derived from the Internal region of human DOCK 2.
Immunogen Region:Internal
Specificity:DOCK 2 Polyclonal Antibody detects endogenous levels of DOCK 2 protein.
Function Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Protein Name Dedicator Of Cytokinesis Protein 2
Database Links Reactome: R-HSA-164944
Reactome: R-HSA-6798695
Reactome: R-HSA-8980692
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-983231
Cellular Localisation Endomembrane System
Peripheral Membrane Protein
Cytoplasm
Cytoskeleton
Colocalizes With F-Actin
Alternative Antibody Names Anti-Dedicator Of Cytokinesis Protein 2 antibody
Anti-DOCK2 antibody
Anti-KIAA0209 antibody

Information sourced from Uniprot.org