| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Double C2-like domain-containing protein alpha (22-72 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DOC2A |
| Gene ID: |
8448 |
| Uniprot ID: |
DOC2A_HUMAN |
| Immunogen Region: |
22-72 aa |
| Specificity: |
This antibody detects endogenous levels of DOC2A at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human DOC2A at the amino acid range 22-72 |
| Function | Calcium sensor which most probably regulates fusion of vesicles with membranes. Binds calcium and phospholipids. May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A. May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells. |
| Protein Name | Double C2-Like Domain-Containing Protein AlphaDoc2Doc2-Alpha |
| Cellular Localisation | LysosomeCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembranePeripheral Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Double C2-Like Domain-Containing Protein Alpha antibodyAnti-Doc2 antibodyAnti-Doc2-Alpha antibodyAnti-DOC2A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
