Anti-DNTTIP2 antibody (1-300) (STJ118560)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DNTTIP2 (1-300) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DNTTIP2 |
| Gene ID | 30836 |
| Uniprot ID | TDIF2_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MVVTRSARAKASIQAASAES SGQKSFAANGIQAHPESSTG SDARTTAESQTTGKQSLIPR TPKARKRKSRTTGSLPKGTE PSTDGETSEAESNYSVSEHH DTILRVTRRRQILIACSPVS SVRKKPKVTPTKESYTEEIV SEAESHVSGISRIVLPTEKT TGARRSKAKSLTDPSQESHT EAISDAETSSSDISFSGIAT RRTRSMQRKLKAQTEKKDSK IVPGNEKQIVGTPVNSEDS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DNTTIP2 (NP_055412.2). |
Additional Info
| Tissue Specificity | Widely expressed with higher levels in testis. |
| Function | Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Deoxynucleotidyltransferase Terminal-Interacting Protein 2Estrogen Receptor-Binding ProteinLpts-Interacting Protein 2Lpts-Rp2Terminal Deoxynucleotidyltransferase-Interacting Factor 2Tdif2Tdt-Interacting Factor 2 |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Deoxynucleotidyltransferase Terminal-Interacting Protein 2 antibodyAnti-Estrogen Receptor-Binding Protein antibodyAnti-Lpts-Interacting Protein 2 antibodyAnti-Lpts-Rp2 antibodyAnti-Terminal Deoxynucleotidyltransferase-Interacting Factor 2 antibodyAnti-Tdif2 antibodyAnti-Tdt-Interacting Factor 2 antibodyAnti-DNTTIP2 antibodyAnti-ERBP antibodyAnti-TDIF2 antibody |
Information sourced from Uniprot.org